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Slay the Spire 2 Relic Tier List — Every Relic Ranked

Every relic in Slay the Spire 2 ranked from S-tier powerhouses to situational picks, with detailed analysis of Ice Cream, Wax Relics, boss relic replacements, and which ones to avoid.

Slay the Spire 2 gameplay screenshot showing the card battle interface and relic system

Slay the Spire 2 Card Database - All 567 Cards Complete interactive database of all 567 cards in Slay the Spire 2. Search by name, filter by class (Ironclad, Silent, Defect, Regent, Necrobinder, Colorless), type (Attack, Skill, Power), rarity (Common, Uncommon, Rare, Special), and keywords. Sort cards alphabetically or by cost. Each card displays its full description, energy cost, and high-quality image. Essential tool for deck planning, card discovery, and understanding synergies across all characters.

Slay the Spire 2 Relic Database - All 175 Relics Complete interactive database of all 175 relics in Slay the Spire 2. Filter by character pool (Any, Ironclad, Silent, Defect, Watcher), rarity (Common, Uncommon, Rare, Boss, Event, Shop, Starter), and 37 mechanic tags. Each relic displays tier grades per character (S+ to F), mechanic tags, and full effect descriptions. Sort by name or rarity. Essential for prioritizing relic pickups and understanding character-specific synergies during runs.

Slay the Spire 2 Complete Guide Hub Your ultimate resource for Slay the Spire 2. Find complete character guides, boss strategies, deck building tips, and advanced techniques all in one place.


Slay the Spire 2 Relic Tier List — Every Relic Ranked

Relics are the backbone of every winning run in Slay the Spire 2. Unlike cards, you can’t draft relics on demand — you take what the game offers and adapt. Knowing which relics are universally broken, which are quietly solid, and which are outright traps is the fastest way to stop losing runs that felt like they should have worked.

This tier list covers universal relics (all classes), character-specific standouts, the new Wax Relic system, and the relics you should think twice about picking up. Based on EA v1.0 (March 2026).


Table of Contents

  1. How Relics Work in Slay the Spire 2
  2. S-Tier: Run-Defining Picks You Almost Always Take
  3. A-Tier: Consistent Upgrades Across Most Decks
  4. B-Tier: Solid Relics That Need the Right Context
  5. C-Tier: Situational Picks With Narrow Value Windows
  6. Character-Specific Best Relics by Class
  7. The Wax Relic System Explained
  8. Trap Relics to Avoid
  9. How to Evaluate Any Relic Mid-Run

How Relics Work in Slay the Spire 2

Relics are passive items that persist for the entire run and activate automatically based on triggers. STS2 has over 150 relics divided into seven categories: Common, Uncommon, Rare, Shop, Event, Ancient, and Starter.

Key changes from STS1:

  • Boss Relics are gone. Replaced by the Ancients system — act-gating entities who offer Blessings (similar in power level).
  • Wax Relics introduced. Temporary relics from Act 2’s Ancient Tezcatara that melt after 3 battles each.
  • Ancient Relics trigger immediately on pickup for one-time effects — they essentially pay their value upfront.

This tier list ranks relics by universal run value across all classes. Some relics with narrow but exceptional synergy appear in the character-specific section instead.


S-Tier: Run-Defining Picks You Almost Always Take

These relics will warp your run in the best possible way. The decision to take them is rarely wrong.

RelicRarityEffectWhy It’s S-Tier
Ice CreamUncommonUnused energy carries over to the next turn.Enables burst rounds, converts wasted energy into a resource, works in every archetype. Consensus pick for strongest universal relic.
Gambling ChipUncommonAt battle start, discard any number of cards and redraw the same amount.Fixes bad opening hands every single fight. Especially broken with Silent’s Sly cards.
Paper PhrogRareVulnerable enemies take 75% more damage (up from 50%).Multiplicative damage math. Any Vulnerable application becomes a massive damage amplifier.
Bag of PreparationCommonDraw 2 extra cards at battle start.Free card advantage, no conditions, works every fight. One of the safest S-tier picks in the game.
Tungsten RodUncommonAll HP loss is reduced by 1.Counters Corrosion, chip damage, self-damage costs, and status effects. Broadly reduces the many 1-point bleeds STS2 adds.
AstrolabeAncientOn pickup, Transform and Upgrade 3 cards.Pays immediately. Culls weak cards and upgrades the result — instant deck quality spike.
Arcane ScrollAncientOn pickup, gain a free Rare card.Guarantees a powerful card without using a card reward.
LanternCommonGain 1 extra energy on turn 1.Always-on energy. Universally strong in every deck.
Venerable Tea SetCommonAfter each Rest, start the next battle with 2 extra energy.Massive tempo swing every time you rest.
AnchorCommonGain 10 Block at battle start.Free unconditional defense each fight, no restrictions.

A-Tier: Consistent Upgrades Across Most Decks

Strong relics that pull their weight in most situations. Worth picking unless you already have several S-tier relics covering the same niche.

RelicRarityEffect
Bag of MarblesUncommonApply 1 Vulnerable to all enemies at battle start.
BellowsUncommonUpgrade your entire opening hand for the first turn.
Gremlin HornUncommonWhen an enemy dies, gain 1 Energy and draw 1 card.
Pen NibUncommonEvery 10th attack deals double damage.
Beating RemnantRareRetain your hand at end of turn.
Lizard TailRareWhen HP drops to 0, recover 50% max HP (once per run).
Ornamental FanUncommonEvery 3 Attacks played in a turn grant 4 Block.
Mummified HandUncommonAfter playing a Power card, reduce a random card’s cost by 1 for this battle.
Paper KraneUncommonWeak enemies deal 40% less damage (up from 25%).
Alchemical CofferAncientOn pickup, fill all 4 potion slots.
Archaic ToothAncientOn pickup, Transform and Upgrade a starter card.
PantographUncommonHeal 25 HP at the start of each Boss fight.
AkabekoUncommonGain 8 Vigor at battle start (damage boost for next Attack).
CandelabraUncommonGain 2 Energy at the start of your 2nd turn.
Red MaskUncommonApply 1 Weak to all enemies at battle start.
Mercury HourglassUncommonDeal 3 damage to all enemies at the start of each turn.
PearUncommonOn pickup, increase max HP by 10.
WhetstoneCommonOn pickup, upgrade 2 random Attack cards.
War PaintCommonOn pickup, upgrade 2 random Skill cards.

B-Tier: Solid Relics That Need the Right Context

Good relics with clear value — but their impact scales heavily with deck type and timing. Evaluate against your current build before committing.

RelicRarityEffectContext Needed
Frozen EggUncommonPower cards are auto-upgraded when added to your deck.Power-heavy builds.
Thread and NeedleUncommonGain 4 Plated Armor at battle start.Any defensive build.
VajraCommonGain 1 Strength permanently.Attack-heavy decks.
Oddly Smooth StoneCommonGain 1 Dexterity permanently.Block-focused builds.
NunchakuUncommonEvery 10 Attacks grant 1 Energy.Attack-spam decks.
Letter OpenerUncommonEvery 3 Skills in a turn deal 5 damage to all enemies.Skill-dense decks.
KusarigamaUncommonEvery 3 Attacks in a turn deal 6 to a random enemy.Attack-dense decks.
Stone CrackerUncommonUpgrade 3 random cards at Boss fight start.Any run — free upgrades before the hardest fights.
OrichalcumUncommonIf you end your turn with no Block, gain 6 Block.Aggressive decks that skip block plays.
PendulumCommonDraw 1 card each time your draw pile shuffles.Thin decks with fast cycles.
Regal PillowCommonHeal 15 extra HP when Resting.When you’re frequently choosing to Rest.
Tiny MailboxCommonGain a random potion when you Rest.Consistent potion access alongside Rest healing.
Miniature CannonUncommonUpgraded Attacks deal 3 more damage.Heavily upgraded attack-heavy decks.
Potion BeltCommonGain 2 extra potion slots.Potion-focused builds or long Elite chains.
Bronze ScalesCommonGain 3 Thorns at battle start.Builds facing enemies that attack frequently.
GorgetCommonGain 4 Plated Armor at battle start.Defensive builds; stacks with other Plated sources.
Lucky FyshUncommonGain 15 gold each time you add a card to your deck.Decks expecting to add many cards.

C-Tier: Situational Picks With Narrow Value Windows

These relics are not bad — they’re just highly conditional. Their power depends on a specific deck archetype, current run stage, or unusual build path. Take them only when the conditions are clearly met.

RelicRarityCondition Required
Red SkullCommonIronclad below 50% HP for +3 Strength. Only worth it in deliberate low-HP builds.
Snecko SkullCommonSilent Poison builds only — each Poison application adds 1 stack.
Joss PaperUncommonExhaust-focused decks — draw 1 card per 5 Exhausted cards.
Eternal FeatherUncommonBloated decks — heal 3 HP at Rest per 5 cards in your deck.
Petrified ToadUncommonGenerates a Potion-shaped Stone each battle. The stone’s effect is weak; so is this relic.
Pollinous CoreEventDraw 2 extra cards every 4 turns — only relevant in very long fights.
Bowler HatUncommonGain 20% extra gold — only valuable if you have a lot of gold to multiply.
Juzu BraceletCommon? rooms always trigger events instead of fights — best in Act 1 for avoiding early Elite rooms.
Reptile TrinketUncommonGain 3 Strength when using a potion — requires a potion-heavy strategy.

Slay the Spire 2 gameplay

Character-Specific Best Relics by Class

Ironclad — Best Relics

TierRelicEffect
SDemon TongueFirst HP loss per turn restores equal HP — pairs with self-damage cards like Hemokinesis.
SSelf-Forming ClayGain 3 Block when you lose HP — converts damage into defense.
ARuined HelmetFirst Strength gained per battle is doubled.
BCharon’s AshesDeal 3 damage to all enemies each time you Exhaust a card.
ABurning Blood (Starter)Heal 6 HP after every combat. Smooths out early-act attrition.

Silent — Best Relics

TierRelicEffect
STingshaDeal 3 damage to a random enemy for each card discarded on your turn.
STough BandagesGain 3 Block for each card discarded on your turn.
SHelical DartGain 1 Dexterity per Shiv played this turn.
ASnecko SkullEach Poison applied adds 1 extra stack.
BTwisted FunnelApply 4 Poison to all enemies at battle start.
ARing of the Snake (Starter)Draw 2 extra cards at battle start — best Starter relic in the game for card-draw tempo.

Defect — Best Relics

TierRelicEffect
SData DiskGain 1 Focus at battle start — supercharges all Orb effects.
SRunic CapacitorGain 3 extra Orb slots — enables stacking multiple Orbs simultaneously.
AMetronomeDeal 30 damage to all enemies when you channel your 7th Orb in a battle.
ASymbiotic VirusChannel 1 Dark Orb at battle start.
BGold-Plated CablesRightmost Orb triggers its passive effect twice.
ACracked Core (Starter)Channel 1 Lightning Orb at battle start — useful early, needs Focus to scale.

Regent — Best Relics

TierRelicEffect
SLunar PastryGain 1 Star at end of turn — passive fuel for the Stars engine.
SMini RegentGain 1 Strength the first time you spend Stars each turn.
AFencing ManualForge 10 at battle start (temporary +10 damage on a random card).
AGalactic DustGain 10 Block for every 10 Stars spent.
BRegaliteGain 2 Block whenever you create a Colorless card.
BOrange DoughAdd 2 random Colorless cards to hand at battle start.
ADivine Right (Starter)Gain 3 Stars at battle start — directly powers your core mechanic.

Necrobinder — Best Relics

TierRelicEffect
SUndying SigilIf an enemy’s Doom count ≥ their current HP, they deal 50% less damage.
SFunerary MaskShuffle 3 Soul cards into your draw pile at battle start.
ABook Repair KnifeHeal 3 HP when a non-Minion enemy dies to Doom.
ABone FluteGain 2 Block each time Osty attacks.
BIvory TileGain 1 Soul each time you play a card that costs Souls.
ABound Phylactery (Starter)Summon 1 base unit per turn — critical survival tool in Act 1 given Necrobinder’s low HP.

The Wax Relic System Explained

islay-the-spire-2-relic-tier-list-mage

Wax Relics are temporary relics introduced in Act 2, provided by the Ancient Tezcatara. They melt in order from left to right, with one Wax Relic disappearing every 3 battles.

Slot Priority Strategy:

  • Leftmost slot = weakest Wax Relic (melts first)
  • Rightmost slot = strongest Wax Relic (lasts longest)

When choosing which Wax Relic blessing to accept from Tezcatara:

  • If you’re struggling or running lean, pick the safer consistent option.
  • If your run has good momentum, gamble on high-ceiling options like Golden Path for larger power swings.

Unlike permanent relics, Wax Relics are time-limited investments — factor their remaining turns when deciding how to play around them.


Trap Relics to Avoid

These relics look reasonable in theory but consistently underperform or carry dangerous downside risk.

RelicProblem
Glass CannonDoubles all damage received. In STS2, Piercing attacks bypass Block entirely — making the penalty far more lethal than in STS1. Only consider with reliable Intangible access, which is rare.
Dream CatcherHeals HP when you Rest. The problem: Resting is usually better spent Upgrading cards or Forging. The healing value rarely justifies losing a Rest action.
GiryaSpend up to 3 Rest actions to gain 3 Strength. Three rest actions for 3 Strength is a losing trade in almost all situations.
Tiny HouseGives a bit of HP, max HP, gold, a random card, and upgrades one card. Sounds good, does nothing well. A jack-of-all-trades that rarely outperforms any focused alternative.

How to Evaluate Any Relic Mid-Run

1. Passive vs. Active Passive relics (Anchor, Bag of Marbles, Lantern) generate value every fight without effort. Prioritize them. Active relics need specific conditions met — verify your deck can reliably trigger them before committing.

2. Early vs. Late Run Value

  • Gold-generating relics (Amethyst Aubergine, Lucky Fysh) compound over time — best taken in Act 1.
  • HP-recovery relics (Pantograph) matter most approaching Boss fights — best mid-act.
  • Scaling relics (Akabeko, Vajra) are best taken early when their effects compound across more fights.

3. Relic vs. Gold Generally, relics > gold. A relic provides value across every remaining fight; gold is spent once. Exception: when you’re about to hit a Shop and need a specific card or potion to fix a critical gap.

4. Ancient Relics Are Almost Always Worth Taking Ancient Relics (Astrolabe, Arcane Scroll, Archaic Tooth, Alchemical Coffer) pay their value on pickup. There’s no ongoing condition to meet. The baseline floor is high enough that passing on them is usually a mistake.


Frequently Asked Questions

What is the best relic in Slay the Spire 2?

Ice Cream is widely considered the strongest universal relic. It allows unused energy to carry over to the next turn, enabling explosive burst rounds that can end fights before they become dangerous. Gambling Chip and Paper Phrog compete for the second and third spots depending on your deck.

Are Boss Relics still in Slay the Spire 2?

No. Boss Relics have been removed in STS2. They are replaced by the Ancients system — powerful entities you encounter each act who offer Blessings (buffs) in exchange for completing specific conditions. Wax Relics from Tezcatara are the closest equivalent, functioning as temporary relics that melt after 3 battles each.

What are Wax Relics and how do I use them effectively?

Wax Relics come from the Act 2 Ancient Tezcatara. They melt one-by-one from left to right every 3 battles. The optimal strategy is to place your weakest Wax Relic on the leftmost slot so it burns first, while keeping the strongest ones in the rightmost position to last the longest.

Which relics are traps in Slay the Spire 2?

Glass Cannon is the most dangerous trap — it doubles all damage you receive, and in STS2 Piercing attacks bypass Block entirely, making the downside even more punishing. Tiny House, Dream Catcher, and Girya all sound useful but rarely justify taking over a stronger alternative.

Do character-specific relics only work on their matching class?

Yes. Relics like Red Skull (Ironclad), Snecko Skull (Silent), Data Disk (Defect), Lunar Pastry (Regent), and Funerary Mask (Necrobinder) are designed around each class's unique mechanics. Picking them on the wrong character gives zero value — or even negative value if they take a slot from a universal pick.

About the author

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Editor-in-Chief

Founder and Editor-in-Chief of gameguidesbox.com, began surfing the web in the late 19th century. Passionate about movies, coffee, gaming, and life itself. Favorite games include Titanfall 2, Baldur's Gate 3, Metro, PUBG, and CS2.

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